- Nyfeler, B., and Pichler, W.J. 1997. The lymphocyte transformation test for the diagnosis of drug allergy: sensitivity and specificity. Clin Exp Allergy 27:175-181.
- Schnyder, B., Mauri-Hellweg, D., Zanni, M., Bettens, F., and Pichler, W.J. 1997. Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones. J Clin Invest 100:136-141.
- Zanni, M.P., Mauri-Hellweg, D., Brander, C., Wendland, T., Schnyder, B., Frei, E., von Greyerz, S., Bircher, A., and Pichler, W.J. 1997. Characterization of lidocaine-specific T cells. J Immunol 158:1139-1148.
- Zanni, M.P., von Greyerz, S., Schnyder, B., Brander, K.A., Frutig, K., Hari, Y., Valitutti, S., and Pichler, W.J. 1998. HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes. J Clin Invest 102:1591-1598.
- von Greyerz, S., Zanni, M.P., Frutig, K., Schnyder, B., Burkhart, C., and Pichler, W.J. 1999. Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones. J Immunol 162:595-602.
- Schnyder, B., Burkhart, C., Schnyder-Frutig, K., von Greyerz, S., Naisbitt, D.J., Pirmohamed, M., Park, B.K., and Pichler, W.J. 2000. Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals. J Immunol 164:6647-6654.
- Burkhart, C., Britschgi, M., Strasser, I., Depta, J.P., von Greyerz, S., Barnaba, V., and Pichler, W.J. 2002. Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides. Clin Exp Allergy 32:1635-1643.
- Burkhart, C., von Greyerz, S., Depta, J.P., Naisbitt, D.J., Britschgi, M., Park, K.B., and Pichler, W.J. 2001. Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells. Br J Pharmacol 132:623-630.
- Yawalkar, N., Shrikhande, M., Hari, Y., Nievergelt, H., Braathen, L.R., and Pichler, W.J. 2000. Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions. J Allergy Clin Immunol 106:1171-1176.
- Yawalkar, N., Hari, Y., Frutig, K., Egli, F., Wendland, T., Braathen, L.R., and Pichler, W.J. 2000. T cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug specific and cytotoxic. J Invest Dermatol 115:647-652.
- Hari, Y., Frutig-Schnyder, K., Hurni, M., Yawalkar, N., Zanni, M.P., Schnyder, B., Kappeler, A., von Greyerz, S., Braathen, L.R., and Pichler, W.J. 2001. T cell involvement in cutaneous drug eruptions. Clin Exp Allergy 31:1398-1408.
- Pichler, W.J. 2003. Delayed drug hypersensitivity reactions. Ann Intern Med 139:683-693.
- Pichler, W.J., and Tilch, J. 2004. The lymphocyte transformation test in the diagnosis of drug hypersensitivity.The lymphocyte transformation test in the diagnosis of drug hypersensitivity. Allergy 59:809-820.
- Beeler, A., Engler, O., Gerber, B.O., and Pichler, W.J. 2006. Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions. J Allergy Clin Immunol 117:455-462.
- Schmid, D.A., Depta, J.P., Luthi, M., and Pichler, W.J. 2006. Transfection of drug-specific T-cell receptors into hybridoma cells: tools to monitor drug interaction with T-cell receptors and evaluate cross-reactivity to related compounds. Mol Pharmacol 70:356-365.
- Schmid, D.A., Depta, J.P., and Pichler, W.J. 2006. T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. Clin Exp Allergy 36:59-69.
- Keller, M., Spanou, Z., Schaerli, P., Britschgi, M., Yawalkar, N., Seitz, M., Villiger, P.M., and Pichler, W.J. 2005. T cell-regulated neutrophilic inflammation in autoinflammatory diseases. J Immunol 175:7678-7686.
- Spanou, Z., Keller, M., Britschgi, M., Yawalkar, N., Fehr, T., Neuweiler, J., Gugger, M., Mohaupt, M., and Pichler, W.J. 2006. Involvement of drug-specific T cells in acute drug-induced interstitial nephritis. J Am Soc Nephrol 17:2919-2927.
- Lerch, M., Keller, M., Britschgi, M., Kanny, G., Tache, V., Schmid, D.A., Beeler, A., Gerber, B.O., Luethi, M., Bircher, A., et al. 2007. Cross-reactivity patterns of T cells specific for iodinated contrast media. J Allergy Clin Immunol
- Beeler A, Zaccaria L, Kawabata T, Gerber BO, Pichler WJ. 2008. CD69 upregulation on T cells as an in vitro marker for delayed-type drug hypersensitivity. Allergy 63(2):181-8
- Lochmatter P, Beeler A, Kawabata TT, Gerber BO, Pichler WJ. 2009. Drug-specific in vitro release of IL-2, IL-5, IL-13 and IFN-gamma in patients with delayed-type drug hypersensitivity. Allergy. 64(9):1269-78.
- Lochmatter P, Zawodniak A, Pichler WJ. 2009. In vitro tests in drug hypersensitivity diagnosis Immunol Allergy Clin North Am.29(3):537-54.
